Thomas Hoepker studied art history and archeology, then worked as a photographer for Münchner Illustrierte and Kristall between 1960 and 1963, reporting from all over the world. He joined Stern magazine as a photo-reporter in 1964.

Magnum began to distribute Hoepker’s archive photographs in 1964. He worked as cameraman and producer of documentary films for German television in 1972, and from 1974 collaborated with his wife, the journalist Eva Windmoeller, first in East Germany and then in New York, where they moved to work as correspondents for Stern in 1976. From 1978 to 1981 Hoepker was director of photography for the American edition of Geo.

He was president of Magnum Photos from 2003 to 2006. A retrospective exhibition, showing 230 images from fifty years of work, toured Germany and other parts of Europe in 2007.